Naltrexone Low Dose
Posted on May 12, 2011 by Jeffrey
At 09:02 am this morning I received an alert via Google Alerts. I try to keep my eye out on the happenings with Sarcoidosis but this one caught me off guard. It is another “off label” drug to help combat Sarcoidosis.
I’ve heard of Arthritis medication and Cancer medication as treatments for Sarcoidosis but I have never heard of drugs that are for treating Opiate and Alcohol addiction as treatments for Sarcoidosis.
Naltrexone was approved by the FDA in 1984. Along with counseling and social support to help people who have stopped drinking alcohol and using street drugs continue to avoid drinking or using drugs. Naltrexone should not be used to treat people who are still using street drugs or drinking large amounts of alcohol. Naltrexone is in a class of medications called opiate antagonists. It works by decreasing the craving for alcohol and blocking the effects of opioid medications and opioid street drugs.
Naltrexone may cause liver damage (like most of the drugs prescribed for Sarcoidosis that are really for the treatment of certain cancers) when taken in large doses (but we are talking about Low Doses here). It is not likely that naltrexone will cause liver damage when taken in recommended doses. Tell your doctor if you have or have ever had hepatitis or liver disease. If you experience any of the following symptoms, stop taking naltrexone and call your doctor immediately: excessive tiredness, unusual bleeding or bruising, loss of appetite, pain in the upper right part of your stomach that lasts more than a few days, light-colored bowel movements, dark urine, or yellowing of the skin or eyes. Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests to check your body’s response to naltrexone.Talk to your doctor about the risks of taking naltrexone.
Back in 1985 (only one year after its FDA approval) a doctor in New York City by the name of Bernard Bihari, MD found that in smaller doses (about 3mg a day) affected the immune system. And as we all know Sarcoidosis is a quasi immune system disorder. The lower dose was taken before bed and was proven to be effective in the response in people with HIV. Now the dosage was reconfigured to 4.5mg once per day.
The mid nineties ushered in new patients for Dr. Bihari. Cancer patients namely ones who were afflicted with Lymphoma and those with pancreatic cancers. The people in theses cases benefited dramatically from the new drug. Other people afflicted with another disease were also affected. This also included people like us. People afflicted with Sarcoidosis and other autoimmune diseases. The subjects showed a quick control response to the dosage. There is more to this fascinating ‘New’ (at least for me) find. There is more information below.
Naltrexone Low Dose
The Low Dose Naltrexone Homepage